Formulation: A solid
Formal Name: 2-[(8,9-dimethylthieno[3,2-e]-1,2,4-triazolo[4,3-c]pyrimidin-3-yl)thio]-acetic acid, methyl ester
Purity: ≥98%
Formula Markup: C12H12N4O2S2
Formula Weight: 308,4
Shelf life (days): 1095
CAS Number: 335401-44-0
Notes: BDW568 is an agonist of stimulator of interferon genes (STING) and a prodrug form of BDW-OH.{67588} It induces STING transcriptional activity in a reporter assay using THP-1 cells (EC50 = 7.6 µM). BDW568 (50 µM) induces phosphorylation of TANK-binding kinase 1 (TBK1) and IFN regulatory factor 3 (IRF3) in THP-1 cells.