Bitertanol, CAS 55179-31-2

Formulation: A solid

Formal Name: β-([1,1'-biphenyl]-4-yloxy)-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol

Purity: ≥98%

Formula Markup: C20H23N3O2

Formula Weight: 337,4

Shelf life (days): 1460

CAS Number: 55179-31-2

Notes: Bitertanol is a broad-spectrum triazole fungicide that is active against a variety of fungi, including V. inaequalis and V. pirina, which are responsible for apple and pear scab, respectively, as well as S. mors-uvae and P. ribis, which are responsible for American gooseberry mildew and leaf spot in black currants, respectively.{39670} It is active against isolates of V. inaequalis (MICs = 0.6 and 1 µg/ml) but repeated use leads to resistance and cross-resistance (MICs = 9.8-13 µg/ml for bitertanol-resistant isolates).{39671} Bitertanol inhibits the cytochrome P450 (CYP450) isoform CYP3A4 (IC50 = 2.74 µM) and inhibits androgenic activity induced by the androgen receptor agonist DHT (Item No. 15874) in a yeast two-hybrid assay (IC50 = 79.85 µM).{39672} In rats, bitertanol (10-300 mg/kg, i.p.) increases operant responding on one- and five-minute fixed interval schedules with no effect on motor activity.{39673}

• SKU: CAY24054-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24054-500
• Green Labware: No
• Package Unit: 500 mg
• Quantity Unit: STK