Centrinone, CAS 1798871-30-3

Formulation: A solid

Formal Name: 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine

Purity: ≥95%

Formula Markup: C26H25F2N7O6S2

Formula Weight: 633,6

Shelf life (days): 1460

CAS Number: 1798871-30-3

Notes: Centrinone is an inhibitor of polo-like kinase 4 (Plk4; Ki = 0.16 nM).{57966} It is greater than 1,100- and 2,800-fold selective for Plk4 over Aurora A and Aurora B kinases, respectively, and a panel of 442 kinases at 100 nM. Centrinone (125 nM) depletes centrosomes and induces apoptosis in HeLa cells.

• SKU: CAY24684-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24684-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe