Cilomilast , CAS 153259-65-5

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CAS Number: 153259-65-5

Description: Cilomilast, also known as SB-207499 or Ariflo, is a potent second generation inhibitor of type 4 phosphodiesterase (PDE4), an enzyme metabolizing cellular cyclic adenosine monophosphate (cAMP) which acts as a second messenger to disrupt the function of inflammatory cell and induce airway smooth muscle relaxation.

Solubility: Soluble in DMSO

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Target: PDE4

Biosafety Level: Not applicable (BSL-1)

References: 1. M Profita, et al. Thorax 2003; 58: 573-579.
2. Barry D. et al. J Clin Pharmacol 2001; 41: 950-958.

• SKU: BPS27742-3
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 27742-3
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK