CL2A-SN38, CAS 1279680-68-0

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CAS Number: 1279680-68-0

Description: CL2A-SN38 is a SN38 derivative with a Mal-PEG attached peptide linker, it can easily react with antibody to form an antibody-drug conjugate (ADC). SN-38 is a potent DNA Topoisomerase I inhibitor. CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A linker is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond.

Format: Solid

Storage Stability: At least 6 months at -20°C. 

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

• SKU: BPS82256-1
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 82256-1
• Package Unit: 50 mg
• Quantity Unit: STK