Copanlisib, CAS 1032568-63-0

Formulation: A crystalline solid

Formal Name: 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide

Purity: ≥98%

Formula Markup: C23H28N8O4

Formula Weight: 480,5

Shelf life (days): 1460

CAS Number: 1032568-63-0

Notes: Copanlisib is an inhibitor of class I phosphoinositide 3-kinase (PI3K) isoforms (IC50s = 0.5, 3.7, 6.4, and 0.7 nM for α, β, γ, and δ, respectively).{32958} It is weakly active or inactive against numerous other kinases. Copanlisib is effective in vivo when administered intravenously, inhibiting PI3K signaling and inducing tumor regression via apoptosis in xenograft tumors in mice.{32958,32959}

• SKU: CAY20354-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 20354-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK