COTC, CAS 57449-30-6

Formulation: A solid

Formal Name: 2-butenoic acid, [(3R,4R,5R)-3,4,5-trihydroxy-6-oxo-1-cyclohexen-1-yl]methyl ester

Purity: ≥90%

Formula Markup: C11H14O6

Formula Weight: 242,2

Shelf life (days): 1460

CAS Number: 57449-30-6

Notes: COTC is a bacterial metabolite that has been found in S. griseosporeus and has anticancer activity.{69076} It inhibits glyoxalase in the presence of glutathione (GSH) in a concentration- and time-dependent manner. COTC inhibits the proliferation of HeLa cells (IC50 = 18 µg/ml), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.

• SKU: CAY36408
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36408-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe