Formulation: A crystalline solid
Formal Name: 1-(2,2-dimethylhydrazide)-butanedioic acid
Purity: ≥95%
Formula Markup: C6H12N2O3
Formula Weight: 160,2
Shelf life (days): 1460
CAS Number: 1596-84-5
Notes: Daminozide is an inhibitor of the 2-oxoglutarate histone lysine demethylases KDM2A, PHF8, and KDM7A (IC50s = 1.5, 0.55, and 2.1 µM, respectively) and a plant growth regulator.{21348} It is selective for KDM2A, PHF8, and KDM7A over KDM3-6 (IC50s = >100 µM for all), as well as the additional 2-oxoglutarate oxygenases FIH, EGLN1, and BBOX1 (IC50s = >100 µM for all). It reduces peduncle and internodal elongation in C. officinalis when applied at the visible bud stage at concentrations of 1,500, 3,500, or 5,000 ppm.{51391} Formulations containing daminozide have previously been used in agricultural applications to control plant growth and fruit size.
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