Product Description: DAPT (GSI-IX) (GMP) is DAPT (HY-13027) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DAPT is a potent and orally active γ-secretase inhibitor[1][2].
Applications: Neuroscience-Neurodegeneration
Formula: C23H26F2N2O4
References: [1]Qi Y, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017 Feb;35(2):154-163./[2]Choi IY, et al. Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model. Cell Rep. 2016 Jun 7;15(10):2301-2312.
CAS Number: 208255-80-5
Molecular Weight: 432.46
Research Area: Cancer; Inflammation/Immunology; Neurological Disease