DBCO-acid (GMP), CAS 1353016-70-2

Product Description: DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1]. DBCO-acid is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C19H15NO3

References: [1]Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61.

CAS Number: 1353016-70-2

Molecular Weight: 305.33

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-42972G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-42972G-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK