Product Description: DBCO-amine GMP is a GMP grade DBCO-amine (HY-W000423). DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-amine is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Applications: Cancer-programmed cell death
Formula: C18H16N2O
References: [1]Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.