DBCO-amine (GMP), CAS 1255942-06-3

DBCO-amine (GMP), CAS 1255942-06-3
SKU
MEXHY-W000423G-0
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MedChemExpress

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Product Description: DBCO-amine GMP is a GMP grade DBCO-amine (HY-W000423). DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-amine is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C18H16N2O

References: [1]Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.

CAS Number: 1255942-06-3

Molecular Weight: 276.33

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker
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SKU MEXHY-W000423G-0
Manufacturer MedChemExpress
Manufacturer SKU HY-W000423G-0
Green Labware No
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