DC-05, CAS 890643-16-0

Formulation: A solid

Formal Name: α-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-9H-carbazole-9-ethanol

Purity: ≥98%

Formula Markup: C25H25N3O

Formula Weight: 383,5

Shelf life (days): 1460

CAS Number: 890643-16-0

Notes: DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 10.3 µM).{66105} It is selective for DNMT1 over DNMT3A and DNMT3B (IC50s = >200 µM), as well as the additional methyltransferases G9a, SUV39H1, MLL1, SET7/9, and PRMT1 (IC50s = >150, >150, >150, >150, and 37.1 µM, respectively). DC-05 (2.5-10 µM) reduces proliferation of HCT116 colon cancer cells.

• SKU: CAY36584-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36584-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe