Product Description: Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs)[1][2].
Applications: Cancer-Kinase/protease
Formula: C24H27Cl2N5O
References: [1]Fjodorova, Marija, et al. Robust Induction of DARPP32-Expressing GABAergic Striatal Neurons from Human Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.) vol. 1780 (2018): 585-605./[2]Piragyte, Indre et al. A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nature communications vol. 9,1 3090. 6 Aug. 2018.
CAS Number: 1219168-18-9
Molecular Weight: 472.41
Research Area: Cancer; Neurological Disease
Solubility: 10 mM in DMSO
Target: AMPK