Formulation: A solid
Formal Name: tert-butyl ((7S)-3r-((2-(5R,6-difluoroisoindolin-2-yl)-2-oxoethyl)amino)adamantan-1s-yl)carbamate
Purity: ≥95%
Formula Markup: C25H33F2N3O3
Formula Weight: 461,7
Shelf life (days): 1460
Notes: DPP-9 inhibitor 42 is an inhibitor of dipeptidyl peptidase 9 (DDP-9; IC50 = 0.0034 µM).{67769} It is selective for DDP-9 over DPP-8, DPP-4, DPP-2, fibroblast activation protein (FAP), and prolyl endopeptidase (IC50s = 0.6, >10, >5, 10, and >10 µM, respectively). DPP-9 inhibitor 42 (10 µM) induces lactate dehydrogenase (LDH) release from THP-1 acute monocytic and HL-60 promyeloblast leukemia cells.