DSRM-3716, CAS 58142-99-7

Formulation: A solid

Formal Name: 5-iodo-isoquinoline

Purity: ≥95%

Formula Markup: C9H6IN

Formula Weight: 255,1

Shelf life (days): 1460

CAS Number: 58142-99-7

Notes: DSRM-3716 is an inhibitor of the axonal degeneration mediator and NADase sterile alpha and TIR motif containing 1 (SARM1; IC50 = 75 nM).{67619} It decreases levels of cyclic ADP ribose (cADPR) and increases NAD+ levels in axotomized primary mouse dorsal root ganglia (DRG) axons when used at concentrations ranging from 1.1 to 30 µM. DSRM-3716 (0.1-10 µM) prevents axonal degeneration in primary wild-type but not Sarm1-/- axotomized DRG axons.

• SKU: CAY39517-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39517-1
• Package Unit: 1 g
• Quantity Unit: STK