Formulation: A solid
Formal Name: N-[2-[4-[(aminosulfonyl)oxy]phenyl]ethyl]-tetradecanamide
Purity: ≥95%
Formula Markup: C22H38N2O4S
Formula Weight: 426,6
Shelf life (days): 1095
CAS Number: 186303-55-9
Notes: DU-14 is a steroid sulfatase inhibitor (IC50 = 55.8 nM).{49827} It inhibits the proliferation of MCF-7 breast cancer cells (IC50 = 38.7 nM).{49828} In vivo, DU-14 (30 mg/kg), in combination with the steroid precursor dehydroepiandrosterone sulfate (DHEAS; Item No. 15873), potentiates DHEAS reversal of scopolamine-induced amnesia in the passive avoidance test in rats.{49827} It also prevents scopolamine-induced amnesia in the passive avoidance test in rats when administered at a dose of 30 mg/kg per day.{49829}