Flumazenil, CAS 78755-81-4

Benzodiazepine antagonist

Product Type: Antagonist

CAS No.: 78755-81-4

MolecularFormula: C15H14FN3O3

Molecular Weight: 303,3

Source: Synthetic

Purity: >98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (8 mg/ml)

Appearance: White powder

PubChem CID: 3373

Scientific Background: A benzodiazepine antagonist1, panspecific for 1,, or5-containing GABAA receptors2. Reduces withdrawal sequelae in benzodiazepine dependence3. Reverses the toxic effects, including coma and respiratory depression of zolpidem intoxication4 and gabapentin-induced coma5.

References: 1. Möhler H., et al. (1981) J. Neurochem. 37:714.2. Doble A., (1999) J. Psychopharmacol. 13(4 Suppl 1):S11.3. Hood SD., et al. (2014) Br. J. Clin. Pharmacol. 77:285.4. Lheureux P., et al.(1990) Hum. Exp. Toxicol. 9:105.5. Masciullo M., et al. (2021) J. Med. Case Rep. 15:242.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-622-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-622-50MG
• Package Unit: 50 mg
• Quantity Unit: STK