Formulation: A solid
Formal Name: N-[1-[[3-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6-trichlorobenzoyl)amino]-1H-pyrazole-3-carboxamide
Purity: ≥95%
Formula Markup: C28H30Cl3N7O5S
Formula Weight: 683
Shelf life (days): 1460
CAS Number: 2364489-81-4
Notes: FMF-04-159-2 is an inhibitor of TAIRE family kinases.{67700} It binds to Cdk14 and Cdk16 (IC50s = 88 and 10.1 nM, respectively) and selectively inhibits Cdk14, Cdk16, Cdk17, and Cdk18 over a panel of 16 additional kinases at 1 µM but does inhibit Cdk2 and Cdk10 by greater than 70% at 1 µM.