FX11, CAS 213971-34-7

Formulation: A solid

Formal Name: 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic acid

Purity: ≥95%

Formula Markup: C22H22O4

Formula Weight: 350,4

Shelf life (days): 1460

CAS Number: 213971-34-7

Notes: FX11 is an inhibitor of lactate dehydrogenase-A (LDH-A; Ki = 8 µM).{68453} It is selective for LDH-A over GAPDH (Ki = >300 µM). FX11 increases oxygen consumption and the production of reactive oxygen species (ROS), as well as induces cell death in P493-6 lymphoblastoid cells. In vivo, FX11 (42 µg/animal, i.p.) reduces tumor volume in a P493-6 mouse xenograft model. It also reduces tumor weight in a BxPC-3 mouse xenograft model when administered at a dose of 2 mg/kg.{68454}

• SKU: CAY38518-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38518-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK