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CAS Number: 2752-65-0
Description: Gambogic acid is a natural product isolated from the resin of Garcinia hurburyi tree, Gambogic acid is a potent apoptosis inducer. It binds covalently to the regulatory subunit B (SPTSSB) of the serine palmitoyltransferase complex and inhibits de novo sphingolipid biosynthesis. Gambogic acid activates caspases in T47D breast cancer cells and inhibits binding of anti-apoptotic proteins to a BH3 peptide.
Format: Solid
Purity: ≥98%
Storage Stability: At least 6 months at -20°C.
Warnings: Avoid freeze/thaw cycles. See SDS for additional warnings and handling.