GBR 13069 (hydrochloride), CAS 67469-45-8

Formulation: A solid

Formal Name: 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenyl-2-propen-1-yl)-piperazine, dihydrochloride

Purity: ≥98%

Formula Markup: C28H30F2N2O • 2HCl

Formula Weight: 521,5

Shelf life (days): 1460

CAS Number: 67469-45-8

Notes: GBR 13069 is a dopamine uptake inhibitor.{25553} It selectively inhibits dopamine uptake over norepinephrine uptake in rat occipital cortex slices (IC50s = 40 and 800 nM, respectively). GBR 13069 (2.5, 5, and 10 mg/kg) induces ipsilateral rotation and increases locomotion in rats. It also prevents 2’-CH3-MPTP-induced decreases in neostriatal levels of the endogenous catecholamine dopamine (Item No. 36532) and its metabolites DOPAC (3,4-dihydroxyphenylacetic acid; Item No. 24912) and homovanillic acid (HVA; Item No. 27307) in mice when administered at a dose of 5 mg/kg.{68485}

• SKU: CAY38903-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38903-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK