GNE-140, CAS 2003234-63-5

Formulation: A solid

Formal Name: 3-[(2-chlorophenyl)thio]-5,6R-dihydro-4-hydroxy-6-[4-(4-morpholinyl)phenyl]-6-(3-thienyl)-2(1H)-pyridinone

Purity: ≥95%

Formula Markup: C25H23ClN2O3S2

Formula Weight: 499

Shelf life (days): 1460

CAS Number: 2003234-63-5

Notes: GNE-140 is an inhibitor of lactate dehydrogenase A (LDHA) and LDHB (IC50s = 3 and 5 nM, respectively).{51603} It reduces lactate production in MiaPaCa-2 pancreatic cancer cells (IC50 = 670 nM). GNE-140 decreases proliferation in a panel of 37 cancer cell lines when used at a concentration of 5 µM.

• SKU: CAY39015-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39015-10
• Package Unit: 10 mg
• Quantity Unit: STK