GSK840, CAS 2361146-30-5

Formulation: A solid

Formal Name: 4-[5-[(methylamino)carbonyl]-1H-benzimidazol-1-yl]-benzeneacetic acid, 1,1-dimethylethyl ester

Purity: ≥98%

Formula Markup: C21H23N3O3

Formula Weight: 365,4

Shelf life (days): 1460

CAS Number: 2361146-30-5

Notes: GSK840 is a receptor-interacting serine/threonine kinase 3 (RIPK3) inhibitor (IC50 = 0.3 nM).{69547} It is selective for RIPK3 over a panel of 300 additional kinases at 1 µM. GSK840 (0.04-1 µM) inhibits TNF-α-induced necroptosis in primary human neutrophils isolated from human whole blood. It also inhibits LPS-induced neutrophil accumulation in D. rerio larvae.{69548}

• SKU: CAY35661-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35661-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK