Guanosine 5'-(γ-thio)triphosphate (sodium salt), CAS 1486471-09-3

Formulation: A solution in water

Formal Name: guanosine 5′-(trihydrogen diphosphate), P′-anhydride with phosphorothioic acid, tetrasodium salt

Purity: ≥95%

Formula Markup: C10H12N5O13P3S • 4Na

Formula Weight: 627,2

Shelf life (days): 730

CAS Number: 1486471-09-3

Notes: Guanosine 5'-[γ-thio]triphosphate (GTPγS) is a hydrolysis-resistant analog of GTP (Item No. 16060) that binds to and activates G proteins in the presence of magnesium.{61910} GTPγS has been used to obtain crystal structures of GTPases in their active states, as well as measure the stability of GTPases in the presence of ligands.{61911,30527} A radiolabeled form of GTPγS, [35S]GTPγS, is commonly used in binding assays to determine agonism or antagonism at G protein-coupled receptors (GPCRs).{61910,61912}

• SKU: CAY38565-2.7
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38565-2.7
• Green Labware: No
• Package Unit: 2,7 mg
• Quantity Unit: STK