ICI 63197, CAS 27277-00-5

Formulation: A solid

Formal Name: 2-amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one

Purity: ≥98%

Formula Markup: C9H13N5O

Formula Weight: 207,2

Shelf life (days): 1460

CAS Number: 27277-00-5

Notes: ICI 63197 is an inhibitor of phosphodiesterase 3 (PDE3) and PDE4 (Kis = 9 and 10 µM, respectively).{68051} It is selective for PDE3 and PDE4 over PDE1 and PDE2 (Kis = 487 and >1,000 µM, respectively). ICI 63197 inhibits acetylcholine-induced bronchospasm in isolated guinea pig lungs and histamine-induced bronchospasm in conscious guinea pigs.{68052} It decreases motor activity and rectal temperature and induces forepaw shaking, head twitches, and grooming in rats in a dose-dependent manner.{68053}

• SKU: CAY35538-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35538-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe