KMH-233, CAS 1941174-13-5

Formulation: A solid

Formal Name: 3-[[[2,4-dicyano-3-[4-[2-(methylamino)-2-oxoethoxy]phenyl]pyrido[1,2-a]benzimidazol-1-yl]amino]carbonyl]-L-phenylalanine

Purity: ≥98%

Formula Markup: C32H25N7O5

Formula Weight: 587,6

Shelf life (days): 1460

CAS Number: 1941174-13-5

Notes: KMH-233 is an inhibitor of L-type amino acid transporter 1 (LAT1; IC50 = 18.2 µM).{59294} It is selective for LAT1 over LAT2 (IC50 = >1,000 µM). KMH-233 (25 and 100 µM) reduces the viability of MCF-7 cells and enhances cell death induced by bestatin (Item Nos. 21217 / 70520) or cisplatin (Item No. 13119) in the same cells. It also reduces mTOR and NF-κB levels and induces apoptosis in MCF-7 cells when used at a concentration of 100 µM.{51762}

• SKU: CAY31032-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 31032-1
• Package Unit: 1 mg
• Quantity Unit: STK