LCS3, CAS 109844-92-0

Formulation: A crystalline solid

Formal Name: N-(4-chlorophenyl)-5-nitro-2-furancarboxamide

Purity: ≥98%

Formula Markup: C11H7ClN2O4

Formula Weight: 266,6

Shelf life (days): 730

CAS Number: 109844-92-0

Notes: LCS3 is an inhibitor of glutathione reductase (GR) and thioredoxin reductase (TrxR; IC50s = 3.3 and 3.8 µM, respectively).{61894} It decreases the glutathione (GSH) to oxidized GSH (GSSG) ratio in NCI H1650 and H23 lung adenocarcinoma cells in a concentration-dependent manner. LCS3 (3 µM) induces apoptosis in NCI H1650 and H23 cells but not non-transformed HPL1D lung epithelial cells. It is also active against M. tuberculosis (MIC = 0.098 µM).{62669}

• SKU: CAY36636-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36636-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe