Loxoprofen (sodium salt), CAS 80382-23-6

Formulation: A solid

Formal Name: α-methyl-4-[(2-oxocyclopentyl)methyl]-benzeneacetic acid, monosodium salt

Purity: ≥98%

Formula Markup: C15H18O3 • Na

Formula Weight: 269,3

Shelf life (days): 1460

CAS Number: 80382-23-6

Notes: Loxoprofen is a non-steroidal anti-inflammatory drug (NSAID) and prodrug form of loxoprofen-SRS.{61942} It inhibits COX-1 and COX-2 in isolated human whole blood (IC50s = 6.5 and 13.5 µM, respectively). Loxoprofen reduces acetic acid-induced writhing in mice and carrageenan-induced paw edema and LPS-induced fever in rats (ED30s = 20.1, 0.7, and 2.79 mg/kg, respectively).{1669} Formulations containing loxoprofen have been used in the treatment of pain associated with osteoarthritis, myalgia, and post-traumatic swelling.

• SKU: CAY35088-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35088-5
• Green Labware: No
• Package Unit: 5 g
• Quantity Unit: STK
• Application: Reinstoffe