Loxoprofen-SRS, CAS 83648-76-4

Formulation: A solid

Formal Name: 4-[[(1R,2S)-2-hydroxycyclopentyl]methyl]-αS-methyl-benzeneacetic acid

Purity: ≥98%

Formula Markup: C15H20O3

CAS Number: 83648-76-4

Notes: Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen (Item No. 35088).{61942} Intravenous administration of loxoprofen-SRS inhibits acetic acid-induced writhing, reduces carrageenan-induced mechanical hyperalgesia, and decreases carrageenan-induced paw edema in rats (ED50s = 0.43, 1.28, and 8.01 mg/kg, respectively).{72305}

• SKU: CAY38122-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38122-10
• Package Unit: 10 mg
• Quantity Unit: STK