LQZ-7I, CAS 195822-23-2

Formulation: A solid

Formal Name: N2,N3-bis(4-fluorophenyl)-2,3-quinoxalinediamine

Purity: ≥98%

Formula Markup: C20H14F2N4

Formula Weight: 348,4

Shelf life (days): 1460

CAS Number: 195822-23-2

Notes: LQZ-7I is an inhibitor of survivin.{66066} It inhibits survivin dimerization in a secreted alkaline phosphatase (SEAP) assay using DU145 prostate cancer cells expressing survivin and induces survivin degradation in C4-2 and PC3 prostate cancer cells in a proteasome-dependent manner. LQZ-7I is cytotoxic to C4-2 and PC3 cells (IC50s = 3.1 and 4.8 µM, respectively). It reduces tumor growth in a PC3 mouse xenograft model when administered at a dose of 100 mg/kg.

• SKU: CAY36602-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36602-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe