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CAS Number: 474645-27-7
Description: MMAE is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. Monomethyl auristatin E or MMAE is 100-1000 times more potent than doxorubicin. It is a very potent antimitotic agent that inhibits cell division by blocking the polymerization of tubulin.
Format: Solid
Purity: 0,95
Solubility: DMSO
Storage Stability: At least 6 months at -20°C.
Warnings: Avoid freeze/thaw cycles. At least 6 months at -20°C. See SDS for additional warnings and handling.