Product Description: Monomethyl auristatin E (MMAE) (GMP) is Monomethyl auristatin E (HY-15162) produced by using GMP guidelines. Monomethyl auristatin E is a tubulin polymerization inhibitor[1].
Applications: Cancer-programmed cell death
Formula: C39H67N5O7
References: [1]Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.
CAS Number: 474645-27-7
Molecular Weight: 717.98
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: ADC Cytotoxin;Apoptosis;Microtubule/Tubulin