Product Type: Antagonist
CAS No.: 357-08-4
MolecularFormula: C19H21NO4 • HCl
Molecular Weight: 363,8
Source: Synthetic
Purity: >98% (HPLC); NMR (Conforms)
Solubility: May be dissolved in DMSO (35 mg/ml); water (30 mg/ml)
Appearance: White crystalline powder
PubChem CID: 5464092
Scientific Background: Pan-opioid receptor antagonist (1). In clinical use in opiate abuse and overdose rescue (2). Blocks opiate- promoted wound healing (3). Attenuates the pruritic response to rimonabant in a rat model (4).
References: 1. Le Bourdonnec B.,et al. (2008)Bioorg. Med. Chem. Lett. 18:2006.2. EW., Boyer (2012) New Engl. J. Med. 367:146.3. WangY., et al. (2017) Transl. Res. 185:13.4. Wright FL., and RJ Rodgers (2013) Psychopharmacology (Berl.) 226:415.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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