Oltipraz (GMP), CAS 64224-21-1

Product Description: Oltipraz (GMP) is Oltipraz (HY-12519) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Oltipraz has an inhibitory effect on HIF-1α activation. Oltipraz is a potent Nrf2 activator[1][2].

Formula: C8H6N2S3

References: [1]Lee WH, et al. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. Mol Cancer Ther. 2009 Oct;8(10):2791-802./[2]Eba S, et al.The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice.Am J Respir Cell Mol Biol. 2013 Aug;49(2):324-33.

CAS Number: 64224-21-1

Molecular Weight: 226.34

Research Area: Cancer

Target: HIF/HIF Prolyl-Hydroxylase;HIV;Keap1-Nrf2;Parasite

• SKU: MEXHY-12519G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12519G-0
• Package Unit: Get quote
• Quantity Unit: STK