Formulation: A solid
Formal Name: 2,2′,5,5′-tetrahydroxy-4,4′-dimethyl-[bi-1,4-cyclohexadien-1-yl]-3,3′,6,6′-tetrone
Purity: ≥70%
Formula Markup: C14H10O8
Formula Weight: 306,2
Shelf life (days): 1460
CAS Number: 475-54-7
Notes: Oosporein is a mycotoxin that has been found in Beauveria and has diverse biological activities.{53467,46283} It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 µM, respectively.{46284} Oosporin induces lethality in day-old cockerels (LD50 = 6.12 mg/kg).{53468} It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 µg/ml.{46283} Oosporein inhibits herpes simplex 1 (HSV-1), but not HeLa cell or E. coli, DNA polymerase (IC50s = 75, 610, and >700 µM, respectively).{53469} It is active against the bacterium S. pneumoniae (MIC = 32 µg/ml) and the plant pathogenic fungus P. infestans (MIC = 16 µM).{53467,53470}
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