OT-82, CAS 1800487-55-1

Formulation: A solid

Formal Name: 3-[2-(4-fluorophenyl)ethynyl]-N-[3-(1H-pyrazol-4-yl)propyl]-4-(4-pyridinyl)-benzamide

Purity: ≥98%

Formula Markup: C26H21FN4O

Formula Weight: 424,5

Shelf life (days): 1460

CAS Number: 1800487-55-1

Notes: OT-82 is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor.{51681} It inhibits recombinant human and recombinant mouse Nampt in a cell-free assay when used at concentrations ranging from 0.1 to 10 µM. OT-82 is cytotoxic against a panel of 12 hematological cancer cells (IC50s = 1.01-5.64 nM). In vivo, OT-82 (25 and 50 mg/kg) increases survival and decreases tumor volume in MV4-11 and HEL 92.1.7 mouse xenograft models.

• SKU: CAY38782-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38782-5
• Package Unit: 5 mg
• Quantity Unit: STK