PF-00489791, CAS 853003-48-2

Formulation: A solid

Formal Name: 1-(2-ethoxyethyl)-5-(ethylmethylamino)-7-[(4-methyl-2-pyridinyl)amino]-N-(methylsulfonyl)-1H-pyrazolo[4,3-d]pyrimidine-3-carboxamide

Purity: ≥98%

Formula Markup: C20H28N8O4S

Formula Weight: 476,6

Shelf life (days): 1460

CAS Number: 853003-48-2

Notes: PF-00489791 is an inhibitor of phosphodiesterase 5A (PDE5A; IC50 = 1.9 nM).{51688} It does not cross the blood-brain barrier in rats. PF-00489791 (10 mg/kg) improves motor scores in a rat model of stroke induced by middle cerebral artery occlusion (MCAO).

• SKU: CAY40464-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40464-25
• Package Unit: 25 mg
• Quantity Unit: STK