Formulation: A solid
Formal Name: 2-(2-pyridinyl)hydrazide, 2-pyridinecarboxylic acid
Purity: ≥95%
Formula Markup: C11H10N4O
Formula Weight: 214,2
Shelf life (days): 1460
CAS Number: 53995-62-3
Notes: PFI-90 is an inhibitor of lysine demethylases (KDMs).{69649} It inhibits KDM3B, KDM4B, KDM5A, and KDM6B by 46.8 to 87.1% when used at a concentration of 10 µM. PFI-90 induces cell death in SJSA-1 osteosarcoma and TC-32 Ewing's sarcoma cancer cells (IC50s = 2 and 1 µM, respectively).