PFM01, CAS 1558598-41-6

Formulation: A solid

Formal Name: 5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone

Purity: ≥98%

Formula Markup: C14H15NO2S2

Formula Weight: 293,4

Shelf life (days): 1460

CAS Number: 1558598-41-6

Notes: PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein Mre11.{61915} It decreases the number of chromosomal breaks in 1BR3 fibroblasts induced by knockdown of BRCA2. PFM01 (50 µM) reduces homologous recombination-mediated DNA repair in DR-GFP U2OS cells and enhances DNA repair mediated by non-homologous end-joining (NHEJ) in H1299 dA3 cells.

• SKU: CAY36574-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36574-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK
• Application: Reinstoffe