Formulation: A solid
Formal Name: 4,4′-[(1R,3aS,4R,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2-methoxy-phenol
Purity: ≥95%
Formula Markup: C20H22O6
Formula Weight: 358,4
Shelf life (days): 1460
CAS Number: 81446-29-9
Notes: (−)-Pinoresinol is a lignan that has been found in Manihot esculenta and has diverse biological activities.{53792,63081,66170} It scavenges DPPH (Item No. 14805) and ABTS (Item No. 27317) radicals in cell-free assays (EC50s = 0.2 and 0.055 mg/ml, respectively).{53792} (−)-Pinoresinol selectively inhibits 5-lipoxygenase (5-LO) and 15-LO over COX-2 (IC50s = 13.8, 3.5, and >100 µM, respectively).{63081} It also inhibits LPS-induced nitric oxide (NO) production in BV-2 microglial cells (IC50 = 34.25 µM).{66170}