POMHEX, CAS 2004714-34-3

Formulation: A solid

Purity: ≥98%

Formula Markup: C17H30NO9P

Formula Weight: 423,4

Shelf life (days): 1460

CAS Number: 2004714-34-3

Notes: POMHEX is a prodrug form of the β-enolase, also known as enolase-3, inhibitor HEX.{60229} It is converted to HEX by intracellular carboxylesterases and selectively reduces the cell density of ENO1-/- D-423MG glioblastoma cells (IC50 = 38 nM) over ENO1-overexpressing D-423MG cells and LN-319 astrocytoma cells expressing wild-type ENO1 (IC50s = 604 and 2,148 nM, respectively). POMHEX decreases cell density in normoxic and hypoxic growth conditions in ENO1-/- D-423MG cells (IC50s = 79 and 201 nM, respectively).

• SKU: CAY33390-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33390-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK