Propacetamol (hydrochloride), CAS 66532-86-3

Formulation: A solid

Formal Name: N,N-diethyl-glycine, 4-(acetylamino)phenyl ester, monohydrochloride

Purity: ≥90%

Formula Markup: C14H20N2O3 • HCl

Formula Weight: 300,8

Shelf life (days): 1460

CAS Number: 66532-86-3

Notes: Propacetamol is a prodrug form of the analgesic and antipyretic agent acetaminophen (Item No. 10024).{64719} It is converted to acetaminophen by rat liver microsomes. Propacetamol reduces acetic acid-induced writhing in mice and LPS-induced pyresis in rats when administered at doses of 200 and 600 mg/kg, respectively.{64719,64720} Propacetamol (1,200 mg/kg) induces hepatotoxicity, decreases hepatic glutathione (GSH), superoxide dismutase (SOD), and glutathione peroxidase (GPX) levels, increases hepatic malondialdehyde (MDA) and nitrotyrosine levels, and increases mortality in mice.{64721}

• SKU: CAY36134-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36134-1
• Green Labware: No
• Package Unit: 1 g
• Quantity Unit: STK
• Application: Reinstoffe