PTP1B-IN-2, CAS 1919853-46-5

Formulation: A solid

Formal Name: 5-[[[4-[(2-methoxy-2-oxoethyl)(methylsulfonyl)amino]phenyl]methyl][(phenylmethyl)sulfonyl]amino]-2-[(4-methylphenyl)methoxy]-benzoic acid, methyl ester

Purity: ≥98%

Formula Markup: C34H36N2O9S2

Formula Weight: 680,8

Shelf life (days): 1460

CAS Number: 1919853-46-5

Notes: PTP1B-IN-2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50 = 50 nM).{66147} It is selective for PTP1B over T cell protein tyrosine phosphatase (TCPTP), Src homology region 2 domain-containing phosphatase 1 (SHP-1), SHP-2, and leukocyte common antigen-related (LAR) phosphatase (IC50s = 760, 2,450, 2,160, and 12,610 nM, respectively). PTP1B-IN-2 (5-20 µM) enhances insulin-induced glucose uptake in L6 myotubes.

• SKU: CAY36824-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36824-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe