RepSox (GMP), CAS 446859-33-2

Product Description: RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C17H13N5

References: [1]Zhao T, et al. Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming. Cell Stem Cell. 2018 Jul 5;23(1):31-45.e7. /[2]Guan J, et al. Chemical reprogramming of human somatic cells to pluripotent stem cells. Nature. 2022 May;605(7909):325-331. /[3]Bar-Nur O, et al. Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors. Stem Cell Reports. 2018 May 8;10(5):1505-1521.

CAS Number: 446859-33-2

Molecular Weight: 287.32

Compound Purity: 99.0

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: TGF-β Receptor

• SKU: MEXHY-13012G-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13012G-50
• Package Unit: 50 mg
• Quantity Unit: STK