SB-431542 (GMP), CAS 301836-41-9

Product Description: SB-431542 (GMP) is SB-431542 (HY-10431) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SB-431542 is a TGF-β receptor kinase inhibitor (TRKI) in SMAD signaling[1][2][3].

Applications: Cancer-Kinase/protease

Formula: C22H16N4O3

References: [1]Yuchen Qi, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017 Feb;35(2):154-163./[2]Tae Wan Kim, et al. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021 Feb 4;28(2):343-355.e5./[3]Monica Nafria, et al. Protocol for the Generation of Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells. STAR Protoc. 2020 Oct 16;1(3):100130.

CAS Number: 301836-41-9

Molecular Weight: 384.39

Compound Purity: 100.2

Research Area: Cancer; Neurological Disease

Solubility: 10 mM in DMSO

Target: TGF-β Receptor

• SKU: MEXHY-10431G-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10431G-50
• Package Unit: 50 mg
• Quantity Unit: STK