SEN-177, CAS 2117405-13-5

Formulation: A solid

Formal Name: 6′-fluoro-2-[4-(4-methyl-4H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3′-bipyridine

Purity: ≥98%

Formula Markup: C18H19FN6

Formula Weight: 338,4

Shelf life (days): 1460

CAS Number: 2117405-13-5

Notes: SEN-177 is a glutaminyl cyclase inhibitor (IC50 = 53 nM).{66671} It reduces polyglutamine aggregation in HeLa cells expressing EGFP-HTT-Q74, an in vitro model of Huntington’s disease when used at concentrations of 12.5 and 25 µM.{66672} SEN-177 (50 µM) reduces polyglutamine aggregation in primary mouse neurons expressing EGFP-Q80.

• SKU: CAY40449-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40449-5
• Package Unit: 5 mg
• Quantity Unit: STK