SGC-CK2-1, CAS 2470424-39-4

Formulation: A solid

Formal Name: N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]-propanamide

Purity: ≥98%

Formula Markup: C20H21N7O

Formula Weight: 375,4

Shelf life (days): 1460

CAS Number: 2470424-39-4

Notes: SGC-CK2-1 is an inhibitor of casein kinase 2α (CK2α; IC50s = 4.2 and 2.3 nM for the catalytic subunits CK2α and CK2α’, respectively).{72140} It is selective for CK2α over DYRK2, Plk4, MEK5, and HIPK1, -2, and -3 (IC50s = 440, >10,000, 1,000, 3,700, 3,400, and 8,100 nM, respectively). SGC-CK2-1 (0.01-10 µM) decreases phosphorylation of Akt in HCT116 cells. See the Structural Genomics Consortium (SGC) website for more information.

• SKU: CAY34103-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34103-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK