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Biological Activity: Sitagliptin as a DPP-4 inhibitor has IC50 value of 18 nM when testing treatment of patients with type 2 diabetes mellitus.
CAS Number: 654671-78-0
Description: Sitagliptin, also known as MK-0431 and Januvia, is a Dipeptidyl Peptidase IV Inhibitor.
Format: White to beige powder.
Purity: ≥98% by NMR
Solubility: Soluble in DMSO.
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: 1. Gallwitz B. Drugs Today (Barc). 2007 Nov; 43(11):801-14
2. Su-Jin Kim et al. Diabetes, 2010 July; 59(7):1739-1750