SP-13786, CAS 1448440-52-5

Formulation: A solid

Formal Name: N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide

Purity: ≥95%

Formula Markup: C17H14F2N4O2

Formula Weight: 344,3

Shelf life (days): 1460

CAS Number: 1448440-52-5

Notes: SP-13786 is an inhibitor of the protease fibroblast activation protein (FAP; IC50 = 3.2 nM).{69964} It is selective for FAP over prolyl endopeptidase, dipeptidyl peptidase 4 (DPP-4), DPP-9, and DPP-2 (IC50s = >1.8, >100, >12.5, and >100 µM, respectively). Nanoliposomes containing a PEGylated form of SP-13786 have been used to target cancer-associated fibroblasts (CAFs) in vitro and in vivo.{69965}

• SKU: CAY41857-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41857-5
• Package Unit: 5 mg
• Quantity Unit: STK