Sp-Thymidine-5'-O-(1-thiotriphosphate) (sodium salt)

Formulation: A solution in water

Formal Name: thymidine, 5′→P′′-ester with [P′′(S)]-thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)), tetrasodium salt

Purity: ≥95%

Formula Markup: C10H13N2O13P3S • 4Na

Formula Weight: 586,2

Shelf life (days): 730

Notes: Sp-Thymidine-5'-O-(1-thiotriphosphate) (Sp-TTP-α-S) is an isomer of the sulfur-containing nucleotide derivative TTP-α-S.{65779} It binds to HIV-1 reverse transcriptase (Kds = 2.88, 4.23, and 20.21 µM in the presence of magnesium, manganate, and cobalt, respectively). Sp-TTP-α-S inhibits deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (Ki = 46 nM).{67439}

• SKU: CAY38690-2.5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38690-2.5
• Green Labware: No
• Package Unit: 2,5 mg
• Quantity Unit: STK